This is supplementary material for:

M. Watts, and A. Sherman. 2014. Modeling the pancreatic alpha-cell: Dual mechanisms of glucose suppression of glucagon secretion, Biophys. J., 106:741-751. [PubMed]

This paper describes intrinsic mechanisms for glucose to control glucagon secretion.

Source files by figure:

• Spiking: Figure 1
• Suppression of glucagon secretion by reducing K(ATP) conductance: Figure 2
• Suppression of glucagon secretion by reducing SOC conductance: Figure 4
• At low glucose, tolbutamide decreases glucagon secretion: Figure 9a
• At high glucose, tolbutamide increases glucagon secretion: Figure 9b