In this model, the Ca2+-activated K+ channel is governed by Ca2+ released from the ER into a small subspace between the ER and the plasma membrane.

Paper 1: Goforth et al, J. Gen. Physiol., 120(3):307-322, September, 2002. [PubMed]

• Model without subspace (Voltage-clamp protocol, Fig. 6) [nosub.ode]
• Model with subspace (Voltage-clamp protocol, Fig. 7). [subspace_pulse.ode]
• Model with subspace (Bursting, Fig. 8). [subspace_burst.ode]
• Model with subspace (Thapsigargin kills bursting, Fig. 9) [tg.ode]

Paper 2: Zhang et al, Biophys. J. 84:2852-2870. 2003. [PubMed]

• First phase for medium and slow cells, Fig. 2 [phase1.ode]
• Steady-state bursting, Fig. 5 [SteadyBursting.ode]
• Noisy single cells (3 types), Fig. 8 [SingleCells.ode]
• Dynamic-clamp conversion of noisy single cell to medium bursting, Fig. 10 [DClamp.ode]