This is supplementary material for:

B. E. Peercy, A. S. Sherman and R. Bertram. 2015. Modeling of glucose-induced cAMP oscillations in pancreatic β-cells: cAMP rocks when metabolism rolls. Biophys. J., 109(2):439-49. [PubMed]

The files are also available at the journal website: [doi]

Readme File [Readme.txt]

Zip archive of all files. [ODEs.zip]

XPP source files by figure:

• [Fig1Left.ode] (Figure 1, left column: Diazoxide (Dz) abolishes cAMP oscillations)

• [Fig1Right.ode] (Figure 1, right column: cAMP oscillations persist in Dz)

• [Fig2.ode] (Figure 2: cAMP oscillations without calcium (Ca) oscillations in Dz plus stimulatory glucose)

• [Fig3.ode] (Figure 3: Rescue of cAMP oscillations terminated by Dz by raising Ca with KCl)

• [Fig4B.ode] (Figure 4B: Fast cAMP oscillations out of phase with Ca oscillations)

• [Fig4C.ode] (Figure 4C: Fast cAMP oscillations in phase with Ca oscillations)

• [Fig5B.ode] (Figure 5B: Compound cAMP oscillations out of phase with Ca oscillations)

• [Fig5C.ode] (Figure 5C: Compound cAMP oscillations in phase with Ca oscillations)