Lab Website at NIDDK

email: arthurs@niddk.nih.gov

### Journal Articles

  1. S. Sivcev, S. Constantin, K. Smiljanic, S. J. Sokanovic, P. A. Fletcher, A. S. Sherman, H. Zemkova, and S. S. Stojilkovic. 2024. Distribution and calcium signaling function of somatostatin receptor subtypes in rat pituitary, Cell Calcium, in press. [doi].

  2. M. Bergman, M. Abdul-Ghani, J. Chan, M. I. Schmidt, J. Ha, S. S. Kim, A. S. Sherman, R. Jagannathan, and J. Tuomilehto. 2024. Staging schema for early diagnosis of prediabetes, Lancet Diabetes Endocrinol., in press. [doi]

  3. J. Ha, J. Y. Kim, M. Springer, A. Chhabra, S. T. Chung, A. E. Sumner, A. Sherman, S. Arslanian. 2024. A Mathematical Model-Derived Disposition Index Without Insulin Validated in Youth with Obesity, J. Clin. Endocrinol. Metab., in press. [PubMed] [doi] [Supplemental Material].

  4. C. B. Kabeza, K. Ntabadde, C. W. DuBose, J. Ha, A. S. Sherman, and A. E. Sumner. 2024. Determining the 1-hour post-load glucose which identifies diabetes in Africans: Insight from the Africans in America study, Diabetes Res Clin Pract., 214:111792. [PubMed] [doi].

  5. J. Haa, S. T. Chunga, M. Springer, J. Y. Kim, P. Chen, A. Chhabra, M. G. Cree, C. Diniz Behn, A. E. Sumner, S. Arslanian, A. S. Sherman. 2023. Estimating Insulin Sensitivity and Beta-Cell Function from the Oral Glucose Tolerance Test: Validation of a new Insulin Sensitivity and Secretion (ISS) Model, Am. J. Physiol. (Endocrinol. Metab.), 326(4):E454-E471. [PubMed] [doi][Matlab and Python Fitting Code] aCo-first authors.

  6. K. B. Dietsche, S. N. Magge, S. A. Dixon, F. S. Davis, A. Krenek, A. Chowdhury, L. Mabundo, M. Stagliano, A. B. Courville, S. Yang, S. Turner, H. Cai, K. Kasturi, A. S. Sherman, J. Ha, E. Shouppe, M. Walter, P. J. Walter, K. Y. Chen, R. J. Brychta, C. Peer, Y. Zeng, W. Figg, F. Cogen, D. E. Estrada, S. Chacko, S. T. Chung. 2023. Glycemia and Gluconeogenesis with Metformin and Liraglutide: A Randomized Trial in Youth-onset Type 2 Diabetes, J. Clin. Endocrinol. Metab., 109(5):1361-1370 [PubMed] [doi].

  7. J. Corradi, B. Thompson, P. A. Fletcher, R. Bertram, A. S. Sherman, L. S. Satin. 2023. KATP channel activity and slow oscillations in pancreatic beta cells are regulated by mitochondrial ATP production. J. Physiol., 601(24):5655-5667 [PubMed] [doi][XPP and Matlab Files].

  8. J. Ha, S. T. Chung, C. Bogardus, R. Jagannathan, M. Bergman, A. S. Sherman. 2023. One-hour glucose is an earlier marker of dysglycemia than two-hour glucose. Diabetes Res Clin Pract., 203:110839 [PubMed] [doi].

  9. A. N. Lorenz, L. Pyle, J. Ha, A. Sherman, M. Cree-Green, S. D. Sagel, K. J. Nadeau, C. L. Chan. 2023. Predictive value of 1-Hour glucose elevations during oral glucose tolerance testing for cystic fibrosis-related diabetes. Pediatric Diabetes, vol. 2023, Article ID 4395556 [doi].

  10. P. A. Fletcher, K. Smiljanic, R. M. Prévide, S. Constantin, A. S. Sherman, S. L. Coon, S. S. Stojilkovic. 2022. The astroglial and stem cell functions of adult rat folliculostellate cells. Glia, 71(2):205-228. [PubMed] [doi].

  11. I. Marinelli, B. M. Thompson, V. S. Parekh, P. A. Fletcher, L. Gerardo-Giorda, A. S. Sherman, L. S. Satin, R. Bertram. 2022. Oscillations in K(ATP) Conductance Drive Slow Calcium Oscillations in Pancreatic β-Cells. Biophys. J. 121(8):1449 - 1464. [PubMed] [doi] [XPP].

  12. S. T. Chung, L. E. Levitt Katz, N. Stettler-Davis, J. Shults, A. Sherman, J. Ha, D. Stefanovski, R. C. Boston, D. J. Rader, S. N. Magge. 2022. The relationship between atherogenic lipoproteins and insulin sensitivity in youth with obesity with and without abnormal glucose tolerance, J. Clin. Endocrinol. Metab. 107(6):1541-1551. [PubMed][doi]

  13. I. Marinelli, V. S. Parekh, P. A. Fletcher, B. Thompson, J. Ren, X. Tang, T. L. Saunders, J. Ha, A. Sherman, R. Bertram, L. S. Satin. 2022. Slow oscillations persist in pancreatic beta cells lacking phosphofructokinase M, Biophys. J., 121:692–704. [PubMed] [doi][XPP File].

  14. M. Kucka, A. Gonzalez-Iglesia, M. Tomic, R. M. Previde, K. Smiljanic, S. J. Sokanovic, P. A. Fletcher, A. Sherman, T. Balla, S. S. Stojilkovic. 2021. Calcium-prolactin secretion coupling in rat pituitary lactotrophs is controlled by PI4-kinase alpha, Front. Endocrinol. 12:790441. [PubMed] [doi]

  15. M. C. S. Ishimwe, A. Wentzel, E. M. Shoup, N. H. Osei-Tutu, T. Hormenu, A. C. Patterson, H. Bagheri, C. W. DuBose, L. S. Mabundo, J. Ha, A. Sherman, A. E. Sumner. 2021. Beta-cell failure rather than insulin resistance is the major cause of abnormal glucose tolerance in Africans: insight from the Africans in America study. BMJ Open Diabetes Res Care, 9(1):e002447. [PubMed] [doi].

  16. J. Ha, R. Muniyappa, A. S. Sherman, and M. J. Quon. 2021. When MINMOD Artifactually Interprets Strong Insulin Secretion as Weak Insulin Action. Front. Physiol. 12:601894. [PubMed] [doi] [XPP and Matlab Files].

  17. R. Jagannathan, C. W. DuBose, L. S. Mabundo, S. T. Chung, J. Ha, A. Sherman, M. Bergman, A. E Sumner. 2020. The OGTT is highly reproducible in Africans for the diagnosis of diabetes: Implications for treatment and protocol design. Diabetes Research and Clinical Practice, 170:108523. [PubMed][doi]

  18. K. Wang, K. Kretschmannova, R.M. Pr'evide, K. Smiljanic, Q. Chen, P.A. Fletcher, A. Sherman, and S.S. Stojilkovic. 2020. Cell Type-Specific Expression Pattern of Proton Sensing Receptors and Channels in Pituitary Gland. Biophys. J., 119(11):2335-2348. [PubMed]

  19. A. F. Hobabagabo, N. H. Osei-Tutu, T. Hormenu, E. M. Shoup, C. W. DuBose, L. S. Mabundo, J. Ha, A. Sherman, S. T. Chung, D. B. Sacks, and A. E. Sumner. 2020. Improved Detection of Abnormal Glucose Tolerance in Africans: The Value of Combining Hemoglobin A 1c With Glycated Albumin. Diabetes Care, 43(10):2607-2613. [PubMed]

  20. R. Muniyappa, H. Chen, M. Montagnani, A. Sherman, and M. Quon. 2020. Endothelial dysfunction due to selective insulin resistance in vascular endothelium: insights from mechanistic modeling. Am. J. Physiol. (Endocrinol. Metab.), 319(3):E629-E646. [PubMed] [Madonna and xpp files]

  21. J. Ha and A. Sherman. 2020. Type 2 Diabetes: One Disease, Many Pathways. Am. J. Physiol. (Endocrinol. Metab.), 319(2):E410-E426. [PubMed] [The Paper] [Matlab and xpp files][Other supplemental material at Figshare] [Highlighted for Diabetes Awareness Month, November, 2020]

  22. S. M. Briker, T. Hormenu, C. W. DuBose, L. S. Mabundo, S. T. Chung, J. Ha, A. Sherman, M. K. Tulloch-Reid, M. Bergman, A. E. Sumner. 2020. Metabolic characteristics of Africans with normal glucose tolerance and elevated 1-hour glucose: insight from the Africans in America study. BMJ Open Diabetes Research and Care. 8(1):e000837. [PubMed]

  23. M. M. Janjic, R. M. Prévide, P. A. Fletcher, A. Sherman, K. Smiljanic, D. Abebe, I. Bjelobaba, and S. S. Stojilkivic. 2019. Divergent expression patterns of pituitary gonadotropin subunit and GnRH receptor genes to continuous GnRH in vitro and in vivo. Sci. Rep. 9(1):20098. [PubMed]

  24. R. T. Scarl, K. L. Corbin, N. W. Vann, H. M. Smith, L. S. Satin, A. Sherman, C. S. Nunemaker. 2019. Intact pancreatic islets and dispersed beta-cells both generate intracellular calcium oscillations but differ in their responsiveness to glucose. Cell Calcium. 83:102081. [PubMed] [R Code].

  25. P. A. Fletcher, K. Smiljanic, R. Maso Prévide, J. Iben, T. Li, M. B. Rokic, A. Sherman, S. L. Coon, and S. S. Stojilkovic. 2019. Cell Type- and Sex-Dependent Transcriptome Profiles of Rat Anterior Pituitary Cells. Front. Endocrinol. 10:623. [PubMed]

  26. S. Briker, J. Aduwo, R. Mugeni, M. F. Horlyck-Romanovsky, C. DuBose, L. Mabundo, T. Hormenu, S. T. Chung, J. Ha, A. Sherman, and A. E. Sumner. 2019. A1C Underperforms as a Diagnostic Test in Africans even in the Absence of Nutritional Deficiencies, Anemia and Hemoglobinopathies: Insight from the Africans in America Study. Front. Endocrinol., Volume 10, Article 533. [PubMed] [The Paper (Open Access)]

  27. S. T. Chung, M. Galvan-De La Cruz, P. C. Aldana, L. S. Mabundo, C. W. DuBose, A. U. Onuzuruike, M. Walter, A. M. Gharib, A. B. Courville, A. S. Sherman, A. E. Sumner. 2019. Postprandial insulin response and clearance among black and white women: The Federal Women’s Study. J. Clin. Endocrinol. Metab., 104(1):181-192. [PubMed] [Commentary]

  28. S. T. Chung, J. Ha, A. U. Onuzuruike, K. Kasturi, M. Galvan De La Cruz, B. A. Bingham, R. L. Baker, J. N. Utumatwishima, L. S. Mabundo, M. Ricks, A. S. Sherman, A. E. Sumner. 2017. Time to Glucose Peak is a Better Indicator of Prediabetes and β-cell function than Shape of the Glucose Curve. Clin. Endocrinol., 87(5):484-491. [PubMed]

  29. L. Mackay, H. Zemkova, S. S. Stojilkovic, A. Sherman, and A. Khadra. 2017. Deciphering the Regulation of P2X4 Receptor Channel Gating by Ivermectin using Markov Models. PLoS Comp. Biol., 13(7):e1005643. [PubMed]

  30. C. H. Ahn, S. H. Min, D.-W. Lee, T. J. Oh, K. M. Kim, J. H. Moon, S. H. Choi, K. S. Park, H. C. Jang, J. Ha and A. Sherman, and S. Lim. 2017. Hemoglobin Glycation Index Is Associated with Cardiovascular Diseases in People with Impaired Glucose Metabolism. J. Clin. Endocrinol. Metab., 102(8):2905-2913. [PubMed]

  31. J. Ha and A. S. Sherman. 2017. How Adaptation Makes Low Firing Rates Robust. J. Math. Neurosci., 7:4. [PubMed] [The Paper (Open Access)] [xpp files]]

  32. N. R. Gandasi, P. Yin, M. Riz, M. V. Chibalina, G. Cortese, P.-E. Lund, V. Matveev, P. Rorsman, A. Sherman, M. G. Pedersen, and S. Barg. 2017. Ca2+ channel clustering with insulin-containing granules is disturbed in type 2 diabetes. J. Clin. Invest., 127(6):2353-2364. [PubMed]

  33. P. A. Fletcher, H. Zemkova, S. S. Stojilkovic, and A. Sherman. 2017. Modeling the diversity of spontaneous and agonist-induced electrical activity in anterior pituitary corticotrophs. J. Neurophysiol., 117(6):2298-2311. [PubMed] [XPP files]

  34. M. Watts, J. Ha, O. Kimchi, and A. Sherman. 2016. Paracrine Regulation of Glucagon Secretion: The β-α-δ Model. Am. J. Physiol. (Endocrinol. Metab.), 310:E597-E611. [PubMed] [XPP Files]

  35. J. P. McKenna, J. Ha, M. J. Merrins, L. S. Satin, A. Sherman, and R. Bertram. 2016. Ca2+ Effects on ATP Production and Consumption Have Key Regulatory Roles on Oscillatory Islet Activity. Biophys. J., 110(3):733-742. [PubMed] [XPP Files]

  36. M. J. Merrins, C. Poudel, J. P. McKenna, J. Ha, A. Sherman, R. Bertram, and L. S. Satin. 2016. Phase Analysis of Metabolic Oscillations and Membrane Potential in Pancreatic Islet β-cells. Biophys. J., 110(3):691-699. [PubMed]

  37. J. Ha, L. S. Satin and A. S. Sherman. 2016. Mathematical Model of the Pathogenesis, Prevention and Reversal of Type 2 Diabetes. Endocrinology, 157(2):624-635. [PubMed] [XPP Files]

  38. E. Glynn, B. Thompson, S. Lu, S. Vadrevu, R. T. Kennedy, J. Ha, A. Sherman and L. S. Satin. 2016. Chronic glucose exposure systematically shifts the oscillatory threshold of mouse islets: Experimental evidence for an early intrinsic mechanism of compensation for hyperglycemia. Endocrinology, 157(2):611-623. [PubMed]

  39. B. E. Peercy, A. S. Sherman and R. Bertram. 2015. Modeling of glucose-induced cAMP oscillations in pancreatic β-cells: cAMP rocks when metabolism rolls. Biophys. J., 109(2):439-49. [PubMed] [XPP Files (also at journal site)]

  40. H. Zemkova, A. Khadra, M. B. Rokic, V. Tvrdonova, A. Sherman and S. S. Stojilkovic. 2015. Allosteric Regulation of the P2X4 Receptor Channel Pore Dilation. Eur. J. Neurosci. (Pflügers Arch.), 467(4):713-726. [PubMed]

  41. B. Eliasson, U. Smith, S. Mullen, S. W. Cushman, A. S. Sherman and J. Yang. 2014. Amelioration of insulin resistance by rosiglitazone is associated with increased adipose cell size in obese type 2 diabetic patients, Adipocyte 3(4):314-321. [PubMed]

  42. M. Watts, B. Fendler, M. J. Merrins, L. S. Satin, R. Bertram, and A. Sherman. 2014. Calcium and metabolic oscillations in pancreatic islets: Who’s driving the bus? SIAM J. Appl. Dyn. Syst. 13(2):683-703. [PubMed] [doi] [XPP Files]

  43. T. McLaughlin, C. Lamendola, N. Coghlan, T. Liu, K. Lerner, A. Sherman, and S. W. Cushman. 2014. Adipose cell size and distribution: Relationships to insulin resistance, body fat, and sex. Obesity, 22(3):673-80. [PubMed]

  44. M. Watts, and A. Sherman. 2014. Modeling the pancreatic alpha-cell: Dual mechanisms of glucose suppression of glucagon secretion, Biophys. J., 106:741-751. [PubMed] [XPP Files]

  45. J. Ren, A. Sherman, R. Bertram, P. B. Goforth, L. S. Satin, C. Waters and C. Nunemaker. 2013. Slow oscillations of KATP conductance in mouse pancreatic islets provide support for electrical bursting driven by metabolic oscillations. Am. J. Physiol. (Endocrinol. and Metab.), 305(7):E805-17. [PubMed] [XPP and Matlab Files]

  46. A. Khadra, M. Tomić, Z. Yan, H. Zemkova, A. Sherman, and S. S. Stojilkovic. 2013. Dual gating mechanism and function of P2X7 receptor channels, Biophys. J., 104(12):2612-2621. [PubMed]

  47. M. J. Merrins, R. Bertram, A. Sherman, and L. S. Satin. 2012. Phosphofructo-2-kinase/Fructose-2,6-bisphosphatase Modulates Oscillations of Pancreatic Islet Metabolism, PLoS One, 7(4):e34036. [PubMed] [XPP Files]

  48. A. Khadra, Z. Yan, C. Coddou, M. Tomić, A. Sherman, and S. S. Stojilkovic. 2012. Gating properties of the P2X2a and P2X2b receptor channels: Experiments and mathematical modeling. J. Gen. Physiol., 139(5):333-348. [PubMed]

  49. J. Yang, B. Eliasson, U. Smith, S. W. Cushman, and A. Sherman. 2012. The size of large adipose cells is a predictor of insulin resistance in first-degree relatives of type 2 diabetic patients. Obesity, 20(5):932-938. [PubMed]

  50. H. M. Osinga, A. Sherman, and K. Tsaneva-Atanasova. 2012. Cross-currents between biology and mathematics: The codimension of pseudo-plateau bursting. Discrete and Continuous Dynamical Systems A, 32(8):2853-2877. [PubMed]

  51. Z. Yan, A. Khadra, A. Sherman, and S. S. Stojilkovic. 2011. Calcium-dependent block of P2X7 receptor channel function is allosteric. J. Gen. Physiol., 138:(4):437-452. [PubMed]

  52. A. Khadra, M. Pietropaolo, G. T. Nepom, and A. Sherman. 2011. Investigating the role of T cell avidity and killing efficacy in relation to type 1 diabetes prediction PLoS One, 6(5):e14796. [PubMed]

  53. M. Watts, J. Tabak, C. Zimliki, A. Sherman, and R. Bertram. 2011. Slow variable dominance and phase resetting in phantom bursting. J. Theor. Biol. 276:218-228. [PubMed] [XPP Files]

  54. A. Liu, A. Sonmez, G. Yee, M. Bazuine, M. Arroyo, A. Sherman, T. McLaughlin, G. Reaven, s. Cushman, P. Tsao. 2010. Differential adipogenic and inflammatory properties of small adipocytes in Zucker Obese and Lean rats. Diab Vasc Dis Res., 7(4):311-8. [PubMed]

  55. Z. Yan, A. Khadra, S. Li, M. Tomic, A. Sherman, and S. S. Stojilkovic. 2010. Experimental characterization and mathematical modeling of P2X7 receptor channel gating. J Neurosci. 30(42):14213-24. [PubMed]

  56. R. Kursawe, M. Eszlinger, D. Narayan, T. Liu, M. Bazuine, A. M. G. Cali, M. Shaw, B. Pierpont, G. I. Shulman, S. W. Cushman, A. Sherman, and S. Caprio. 2010. Cellularity and adipogenic profile of the abdominal subcutaneous adipose tissue from obese adolescents: association with insulin resistance and hepatic steatosis. Diabetes, 59(9):2288-96. [PubMed]

  57. B. E. Peercy and A. S. Sherman. 2010. How pancreatic beta-cells distinguish long- and short-time scale cAMP signals. Biophys. J., 99(2):398-406 [PubMed] [XPP and Matlab Files]

  58. M. J. Merrins, B. Fendler, M. Zhang, A. Sherman, R. Bertram, and L. S. Satin. 2010. Metabolic oscillations in pancreatic islets depend on the intracellular Ca2+ level but not Ca2+ oscillations, Biophys. J., 99:(1)76-94. [PubMed] [XPP Files]

  59. K. Tsaneva-Atanasova, H. M. Osinga, T. Riess, and A. Sherman. 2010. Full system bifurcation analysis of endocrine bursting models. J. Theor. Biol., 264:1133-1146. [PubMed]

  60. T. McLaughlin, G. Yee, T. Liu, F. Abbasi, C. Lamendola, G. Reaven, P. Tsao, S. W. Cushman, and A. Sherman. 2010. Pioglitazone increases the proportion of small cells in human subcutaneous abdominal adipose tissue. Obesity, 18(5):926-31. [PubMed]

  61. T. McLaughlin, A. Deng, G. Yee, C. Lamendola, G. Reaven, P. S. Tsao, S. W. Cushman, and A. Sherman. 2010. Inflammation in subcutaneous adipose tissue: relationship to adipose cell size. Diabetologia 53(2):369-377. [PubMed] [Commentary]

  62. C. S. Nunemaker, J. F. Dishinger, S. B. Dula, R. Wu, M. M. Merrins, K. R. Reid, A. Sherman, R. T. Kennedy, and L. S. Satin. 2009. Glucose metabolism, islet architecture, and genetic homogeneity in imprinting of [C a2+]i and insulin rhythms in mouse islets. PloS One, 4(12):e8428. [PubMed]

  63. A. Liu, T. McLaughlin, T. Liu, A. Sherman, G. Yee, F. Abbasi, C. Lamendola, J. Morton, S. W. Cushman, G. M. Reaven, and P. S. Tsao. 2009 Differential Intra-abdominal Adipose Tissue Profiling in Obese, Insulin-resistant Women. Obes. Surg., 19(11):1564-73. [PubMed]

  64. P. Goel and A. Sherman. 2009. The geometry of bursting in the dual oscillator model of pancreatic beta-cells. SIAM Journal on Applied Dynamical Systems, 8(4):1664-1693. [doi]

  65. V. Matveev, R. Bertram, and A. Sherman. 2009. Ca2+ current vs. Ca2+ channel cooperativity of exocytosis. J. Neurosci., 29(39):12196-12209. [PubMed] [CalC Scripts]

  66. K. Tsaneva-Atanasova and A. Sherman. 2009. Accounting for near-normal glucose sensitivity in Kir6.2[AAA] transgenic mice. Biophys. J. 97(9):2409-18. [PubMed]

  67. P. Goel, A. Sherman, and A. Friedman. 2009. Multiscale modeling of electrical and intracellular activity in the pancreas: The islet tridomain equations. Multiscale Model. Simul., 7(4):1609-1642. [doi]

  68. M. G. Pedersen and A. Sherman. 2009. Newcomer insulin secretory granules as a highly calcium-sensitive pool. PNAS 106(18):7432-6. [PubMed] [xpp files]

  69. T. McLaughlin, A. Deng, O. Gonzales, M. Aillaud, G. Yee, C. Lamendola, F. Abbasi, A. J. Connolly, A. Sherman, S. W. Cushman, G. Reaven, P. S. Tsao. 2008. Insulin resistance is associated with a modest increase in inflammation in subcutaneous adipose tissue of moderately obese women. Diabetologia, 51:2303-8. [PubMed]

  70. M. Zhang, B. Fendler, B. Peercy, P. Goel, R. Bertram, A. S. Sherman, and L. S. Satin. 2008. Long lasting synchronization of calcium oscillations by cholinergic stimulation in isolated pancreatic islets. Biophys. J., 95:4676-4688. [PubMed] [XPP Files]

  71. Y. D. Chen, S. Wang, A. Sherman. 2008. Identifying the targets of the amplifying pathway for insulin secretion in pancreatic beta-cells by kinetic modeling of granule exocytosis. Biophys. J. 95(5):2226-41. [PubMed] [XPP Files]

  72. J. V. Stern, H. M. Osinga, A. LeBeau, and A. Sherman. 2008. Resetting behavior in a model of bursting in secretory pituitary cells: Distinguishing plateaus from pseudo-plateaus. Bull. Math. Biol., 70(1):68-88. [PubMed] [XPP Files]

  73. K. Tsaneva-Atanasova, A. Sherman, F. van Goor, and S. S. Stojilkovic. 2007. Mechanism of spontaneous and receptor-controlled electrical activity in pituitary somatotrophs: Experiments and theory. J. Neurophysiol. 98(1):131-44. [PubMed] [XPP File]

  74. T. McLaughlin, A. Sherman, P. Tsao, O. Gonzalez, G. Yee, C. Lamendola, G. M. Reaven, and S. W. Cushman. 2007. Enhanced proportion of small adipose cells in insulin-resistant versus insulin-sensitive obese individuals implicates impaired adipogenesis. Diabetologia, 50(8):1707-15. [PubMed]

  75. H. L. Ong, X. Liu, K. Tsaneva-Atanasova, B. B. Singh, B. C. Bandyopadhyay, W. D. Swaim, J. T. Russell, R. S. Hegde, A. Sherman, and I. S. Ambudkar. 2007. Relocalization of STIM1 for activation of store-operated Ca2+ entry is determined by the depletion of subplasma membrane endoplasmic reticulum Ca2+ store. J. Biol. Chem., 282(16):12176-85. [PubMed]

  76. R. Bertram, L. S. Satin, M. Gram Pedersen, D. S. Luciani, and A. Sherman, 2007. Interaction of glycolysis and mitochondrial respiration in metabolic oscillations of pancreatic islets. Biophys. J., 92(5):1544-55. [Pubmed] [XPP files]

  77. V. Matveev, R. Bertram, and A. Sherman, 2006. Residual bound Ca2+ can account for the effects of Ca2+ buffers on synaptic facilitation., J. Neurophysiol. 96(6):3389-97 [Pubmed] [CalC Scripts]

  78. R. Bertram, M. Gram Pedersen, D. S. Luciani, and A. Sherman, 2006. A simplified model for mitochondrial ATP production, J. Theor. Biol., 243(4):575-86. [Pubmed] [XPP file]

  79. C. S. Nunemaker, R. Bertram, A. Sherman, K. Tsaneva-Atanosova, C. R. Daniel, and L. S. Satin. 2006. Glucose modulates Ca2+ oscillations in pancreatic islets via ionic and glycolytic mechanisms, Biophys. J., 91:2082-2096. [Pubmed] [XPP Files]

  80. K. Tsaneva-Atanasova, C. L. Zimliki, R. Bertram, and A. Sherman, 2006. Diffusion of calcium and metabolites in pancreatic islets: Killing oscillations with a pitchfork, Biophys. J., 90:3434-3446. [PubMed] [XPP Files]

  81. C. S. Nunemaker, M. Zhang, D. H. Wasserman, O. P. McGuinness, A. C. Powers, R. Bertram, A. Sherman, and L. S. Satin, 2005. Individual mice can be distinguished by the period of their islet calcium oscillations: Is there an intrinsic islet period which is imprinted in vivo? Diabetes, 54:3517-3522 [PubMed]

  82. M. G. Pedersen, R. Bertram, and A. Sherman. 2005. Intra- and Inter-Islet Synchronization of Metabolically Driven Insulin Secretion, Biophys. J., 89:107-119. [PubMed] [XPP Files]

  83. R. Bertram and A. Sherman. 2004. Filtering of calcium transients by the endoplasmic reticulum in pancreatic beta-cells, Biophys. J., 87:3775-3785. [PubMed] [XPP Files]

  84. R. Bertram, L. Satin, M. Zhang, P. Smolen, and A. Sherman. 2004. Calcium and glycolysis mediate multiple bursting modes in pancreatic islets, Biophys. J., 87:3074-3087. [PubMed] [XPP Files and Errata]

  85. R. Bertram and A. Sherman. 2004. A calcium based phantom bursting model for pancreatic beta-cells, Bull. Math. Biol., 66:1313-1344. [PubMed][XPP and Matlab Files]

  86. C. Zimliki, D. Mears, and A. Sherman. 2004. Three roads to islet bursting: Emergent oscillations in coupled phantom bursters, Biophys. J., 87:193-206. [PubMed][XPP file]

  87. V. Matveev, R. S. Zucker, and A. Sherman. 2004. Facilitation through buffer saturation: Constraints on endogenous buffering properties,. Biophys. J. 86:2691-2709. [PubMed] [Calcium Calculator Scripts]

  88. M. Zhang, P. Goforth, A. Sherman, R. Bertram, and L. S. Satin. 2003. The Ca2+ dynamics of isolated mouse beta-cells and islets: Implications for mathematical models, . Biophys. J. 84:2852-2870. [PubMed] [XPP Files]

  89. A. R. Sedaghat, A. Sherman, and M. J. Quon. 2002. A mathematical model of metabolic insulin signaling pathways, Am. J. Physiol. (Endocrinol. Metab.), 283:E1084-E1101. [PubMed] [Supplementary Material: XPP/WinPP Differential Equation Files]

  90. P. B. Goforth, R. Bertram, F. A. Khan, M. Zhang, A. Sherman, and L. S. Satin. 2002. Calcium-activated K+ channels of mouse pancreatic beta-cells are controlled by both store and cytoplasmic Ca2+. J. Gen. Physiol., 120:307-322. [PubMed] [XPP Files]

  91. V. Matveev, A. Sherman, and R. S. Zucker. 2002. New and Corrected Simulations of Synaptic Facilitation, Biophys. J., 83:1368-73. [PubMed] [Simulation Software]

  92. G. de Vries and A. Sherman. 2001. From spikers to bursters via coupling: Help from heterogeneity, Bull. Math. Biol., 63:371-391. [PubMed]

  93. G. D. Smith, L.-X. Dai, R. Miura, and A. Sherman. 2001. Asymptotic analysis of equations for the buffered diffusion of intracellular calcium. SIAM J. Applied Math., 61:1816-1838. [doi] [Matlab Files]

  94. A. P. LeBeau, F. Van Goor, S. S. Stojilkovic, and A. Sherman. 2000. Modeling of membrane excitability in gonadotropin-releasing hormone-secreting hypothalamic neurons regulated by Ca2+-mobilizing and adenylyl cyclase-coupled receptors. J. Neurosci., 20:9290-9297. [PubMed]

  95. G. de Vries and A. Sherman. 2000. Channel sharing in pancreatic beta-cells revisited: Enhancement of emergent bursting by noise. J. Theor. Biol., 207:513-530. [PubMed]

  96. R. Bertram, J. Previte, A. Sherman, T. A. Kinard, and L. S. Satin. 2000. The phantom burster model for pancreatic beta-cells. Biophys. J., 79:2880-2892. [PubMed] [XPP File]

  97. F. Van Goor, A. P. LeBeau, L. Z. Krsmanovic, A. Sherman, K. J. Catt, and S. S. Stojilkovic. 2000. Amplitude-dependent spike-broadening in immortalized GnRH neurons. Biophys. J., 79:1310-1323. [PubMed]

  98. T. A. Kinard, G. de Vries, A. Sherman, and L. S. Satin. 1999. Modulation of the bursting properties of single mouse pancreatic beta-cells by artificial conductances. Biophys. J., 76:1423-1435. [PubMed]

  99. R. Bertram, G. D. Smith, and A. Sherman. 1999. A modeling study of the effects of overlapping Ca2+ microdomains on neurotransmitter release. Biophys. J., 76:735-750. [[PubMed](https://pubmed.ncbi.nlm.nih.gov/9929478/]

  100. G. de Vries, H.-R. Zhu, and A. Sherman. 1998. Diffusively coupled bursters: Effects of heterogeneity. Bull. Math. Biol., 60:1167-1200. [PubMed] [Mathematica Files]

  101. R. Bertram and A. Sherman. 1998. Population dynamics of synaptic release sites. SIAM J. Applied Math., 58:142-169. [doi]

  102. D. Mears, N. F. Sheppard, Jr., I. Atwater, E. Rojas, R. Bertram, and A. Sherman. 1997. Evidence that calcium release-activated current mediates transient glucose-induced electrical activity in the pancreatic beta-cell. J. Membr. Bio., 155:47-59.  [PubMed] [XPP File]

  103. R. Bertram, A. Sherman, and E. Stanley. 1996. The single domain/bound calcium hypothesis of transmitter release and facilitation. J. Neurophysiol., 75:1919-1931.  [PubMed] [XPP File]

  104. R. Bertram, P. Smolen, A. Sherman, D. Mears, I. Atwater, F. Martin, and B. Soria. 1995. A role for calcium-release activated current (CRAC) in cholinergic modulation of electrical activity in pancreatic beta-cells. Biophys. J. 68:2323-2332. [PubMed] [XPP File]

  105. R. Bertram, M. Butte, T. Kiemel, and A. Sherman. 1995. Topological and phenomenological classification of bursting mechanisms. Bull. Math. Biol. 57:413-439. [PubMed] [XPP File]

  106. A. Sherman, L. Xu, and C. Stokes. 1995. Estimating and eliminating junctional current in coupled cell populations by leak subtraction. A computational study. J. Membr. Biol., 143:79-87. [PubMed]  (Joint with experimental paper: E. Rojas, C. Stokes, D. Mears, and I. Atwater. 1995. Single micro-electrode voltage-clamp measurements of pancreatic beta-cell membrane ionic currents in intact mouse islets of Langerhans. J. Membr. Biol. 143:65-77).  [PubMed]

  107. A. Sherman and M. Mascagni. 1994. A gradient random walk method for two-dimensional reaction-diffusion equations. SIAM J. Sci. Comput. 15:1280-1293. [doi]

  108. P. Smolen and A. Sherman. 1994. Phase-independent resetting in relaxation and burst oscillators. J. Theor. Biol. 169:339-348. [PubMed] [XPP File]

  109. A. Sherman. 1994. Anti-phase, asymmetric, and aperiodic oscillations in excitable cells I. Coupled bursters. Bull. Math. Biol. 56:811-835.  [PubMed] [XPP File]

  110. P. Smolen, J. Rinzel, and A. Sherman. 1993. Why pancreatic islets burst but single beta-cells do not: The heterogeneity hypothesis. Biophys. J. 64:1668-1680.   [PubMed]

  111. A. Sherman and J. Rinzel. 1992. Rhythmogenic effects of weak electrotonic coupling in neuronal models. Proc. Natl. Acad. Sci. USA. 89:2471-2474.  [PubMed] [XPP Files]

  112. A. Sherman and J. Rinzel. 1991. Model for synchronization of pancreatic beta-cells by gap junction coupling. Biophys. J. 59:547-559.  [PubMed]

  113. A. Sherman, J. Keizer, and J. Rinzel. 1990. Domain model for Ca2+ inactivation of Ca2+ channels at low channel density. Biophys. J. 58:985-995.  [PubMed] [XPP File]

  114. P. B. Carroll, A. Sherman, R. Ferrer, A. C. Boschero, J. Rinzel, and I. Atwater. 1990. Modulation of the frequency of glucose-dependent bursts of electrical activity by HCO3/CO2 in rodent pancreatic beta-cells. Experimental and theoretical results. Eur. Biophys. J. 18:71-77.  [PubMed]

  115. A. Sherman, J. Rinzel, and J. Keizer. 1988. Emergence of organized bursting in clusters of pancreatic beta-cells by channel sharing. Biophys. J. 54:411-425.   [PubMed] [XPP File]

  116. A. S. Sherman and C. S. Peskin. 1988. Solving the Hodgkin-Huxley equations by a random walk method. SIAM J. Sci. and Stat. Comput. 9:170-190.  [doi]

  117. A. S. Sherman and C. S. Peskin. 1986. A Monte Carlo method for scalar reaction diffusion equations. SIAM J. Sci. and Stat. Comput. 7:1360-1372. [doi]

    Invited Reviews

  118. P. A. Fletcher, I. Marinelli, R. Bertram, L. S. Satin, and A. S. Sherman. 2022. Pulsatile Basal Insulin Secretion is Driven by Glycolytic Oscillations Physiology, 37:216 - 223. [PubMed] [doi] [Cover Art][XPP Code]

  119. B. E. Peercy and A. S. Sherman. 2022. Do oscillations in pancreatic islets require pacemaker cells? J. Biosci., 47:14. [PubMed] [doi]

  120. I. Marinelli, P. A. Fletcher, A. S. Sherman, L. S. Satin, and R. Bertram. 2021. Symbiosis of electrical and metabolic oscillations in pancreatic beta cells. Front. Physiol. 12:781581. [PubMed] [doi] [XPP Code]

  121. R. Bertram, L. S. Satin, and A. S. Sherman. 2018. Closing in on the mechanisms of pulsatile insulin secretion. Diabetes, 67:351-359. [PubMed] [XPP File]

  122. P. A. Fletcher, A. Sherman, and S. S. Stojilkovic. 2018. Common and diverse elements of ion channels and receptors underlying electrical activity in endocrine pituitary cells. Molecular and Cellular Endocrinology, 463:23 - 36. [PubMed] [XPP files]

  123. L. S. Satin, P. C. Butler, J. Ha, and A. Sherman. 2015. Pulsatile insulin secretion, impaired glucose tolerance and type 2 diabetes. Journal of Molecular Aspects of Medicine, 42:61-77. [PubMed]

  124. V. Matveev, R. Bertram, and A. Sherman, 2011. Calcium cooperativity of exocytosis as a measure of Ca2+ channel domain overlap. Brain Research Reviews, 1398:126-128. [PubMed]

  125. A. Sherman, 2010. Lessons from Models of Pancreatic beta Cells for Engineering Glucose-sensing Cells. Math. Biosci., 227:12-19. [PubMed]

  126. R. Bertram, A. Sherman, and L. S. Satin, 2007. Metabolic and electrical oscillations: Partners in controlling pulsatile insulin secretion. Am. J. Physiol. Endocrinol. Metab. 293:890-900. [PubMed]. [XPP File]

  127. G. de Vries and A. Sherman. 2005. Beyond Synchronization: Modulatory and Emergent Effects of Coupling in Square-Wave Bursting in “Bursting: The Genesis of Rhythm in the Nervous System”, World Scientific, London, pp. 243-272. [Publisher’s Site] [doi]

  128. R. Bertram and A. Sherman. 2005. Negative Calcium Feedback: The Road from Chay-Keizer in “Bursting: The Genesis of Rhythm in the Nervous System”, S. Coombes and P. Bressloff, eds., World Scientific, London, pp. 19-48. [Publisher’s Site][doi]

  129. A. Sherman and R. Bertram. 2005. Integrative Modeling of the Pancreatic beta-Cell. in “Wiley Interscience Encyclopedia of Genetics, Genomics, Proteomics, and Bioinformatics”, Part 3 Proteomics, M. Dunn, ed., Section 3.8 Systems Biology, R. L. Winslow, ed., John Wiley & Sons, Ltd. DOI: 10.1002/047001153X.g308213. [On-Line Book] [XPP Files]

  130. A. Sherman. 1996. Contributions of modeling to understanding stimulus-secretion coupling in pancreatic beta-cells. Am. J. Physiol. 271 (Endocrinol. Metab. 34): E362-E372. [PubMed] [XPP File]

  131. A. Sherman. 1995. Theoretical aspects of synchronized bursting in beta-cells, in Pacemaker Activity and Intercellular Communication, J. D. Huizinga, ed., CRC Press, Boca Raton, pp. 323-337.

    Book Chapters & Other Reviews

  132. R. Bertram, I. Marinelli, P. A. Fletcher, L. S. Satin, A. S. Sherman. 2023. Deconstructing the Integrated Oscillator Model for Pancreatic Beta Cells. Math. Biosci., 365:109085. [PubMed] [doi].

  133. L. S. Satin, M. Watts, and A. Sherman. 2020. An introduction to beta cell electrophysiology and modeling, in Diabetes System Biology: Quantitative methods for understanding beta-cell dynamics and function, A. Khadra, editor. IOP Publishing, Bristol, UK, pp. 2-1 - 2-46. [doi] [XPP and Matlab Files]

  134. A. Sherman. 2016. Endoplasmic reticulum- and plasma membrane-driven calcium oscillations, in “Computational Neuroendocrinology” (Wiley-INF Masterclass in Neuroendocrinology Series), D. J. MacGregor and G. Leng, eds., John Wiley & Sons, Chichester, UK, p. 112-141. [The Book] [doi]

  135. R. Bertram, A. Sherman, and L. S. Satin. 2013. Electrical, Calcium, and Metabolic Oscillations in Pancreatic Islets, in “The Islets of Langerhans”, 2nd edition, M. S. Islam, ed., Springer-Verlag, Berlin, p. 453-474. [doi] [The Book]

  136. R. Bertram, A. Sherman, and L. S. Satin. 2010. Electrical Bursting, Calcium Oscillations, and Synchronization of Pancreatic Islets, in “The Islets of Langerhans”, M. S. Islam, ed., Springer-Verlag, Berlin, (Adv Exp Med Biol, 654:261-79). [PubMed] [doi]

  137. R. Bertram, K. Wierschem, M. Zhang, P. Goforth, A. Sherman, and L. S. Satin. 2002. Phantom bursting in pancreatic islets: A potential role for insulin feedback, in “Recent Research Developments in Biophysics”, S. G. Pandalai, ed., Transworld Research Network, Vol. 1, pp. 31-51.

  138. A. Sherman, Y.-X. Li, and J. Keizer. 2002. Whole Cell Models in “Computational Cell Biology”, C. Fall, E. Marland, J. Wagner, and J. Tyson , eds., Springer-Verlag, New York, pp. 101 - 139. [Publisher Site for the Book] [XPP Files]

  139. R. Bertram and A. Sherman. 2000. Dynamical complexity and temporal plasticity in pancreatic beta-cells. J. Biosc., 25:197-209. [PubMed]

  140. M. V. Mascagni and A. S. Sherman. 1998. Numerical methods for neuronal modeling, in “Methods in Neuronal Modeling,” I. Segev and C. Koch, eds., MIT Press, Cambridge, pp.569-606. [The Book] [Supplementary Material]

  141. A. Sherman and P. Smolen. 1997. Computer modeling of heterogeneous beta-cell populations, in “Physiology and Pathophysiology of the Islets of Langerhans”, B. Soria, ed., Plenum Press, New York, pp. 275-284. [PubMed] [doi]

  142. A. Sherman. 1997. Calcium and membrane potential oscillations in pancreatic beta-cells, in “Case Studies in Mathematical Modeling - Ecology, Physiology, and Cell Biology”, H. G. Othmer, F. R. Adler, M. A. Lewis, and J. C. Dallon, eds., Prentice-Hall, New Jersey, p. 199 - 217. [The Book] [Models and Exercises]

  143. J. Rinzel, A. Sherman, and C. L. Stokes. 1992. Channels, coupling, and synchronized rhythmic bursting activity. in “Analysis and Modeling of Neural Systems”, F. H. Eeckman, ed., Kluwer Academic Publishers, Boston, pp. 29-46.

  144. A. Sherman, P. Carroll, R. Santos, and I. Atwater. 1990. Glucose dose response of pancreatic beta-cells: Experimental and theoretical results, in “Transduction in Biological Systems”, J. Bacigalupo, C. Hidalgo, E. Jaimovich, and J. Vergara, eds., Plenum Press, New York, pp. 123-141.

  145. A. Sherman and J. Rinzel. 1989. Collective properties of insulin secreting cells, in “Cell to Cell Signalling: From Experiments to Theoretical Models”, A. Goldbeter, ed., Academic Press, London, pp. 61-75.

    Commentary

  146. L. S. Satin, J. Corradi, A. S. Sherman. 2024. Do We Need a New Hypothesis for KATP Closure in <&beta>-Cells? Distinguishing the Baby From the Bathwater. Diabetes, in press [doi].

  147. A. S. Sherman, P. A. Fletcher, L. S. Satin, R. Bertram. 2023. The Pancreatic Beta Cell: Biology and Mathematics Advance Together, SIAM News, 56(9):1. [Online].

  148. P. A. Fletcher, B. Thompson, C. Liu, R. Bertram, L. S. Satin, A. S. Sherman. 2023. Ca2+ Release or Ca2+ Entry, that is the Question: What Governs Ca2+ Oscillations in Pancreatic Beta Cells?, Am. J. Physiol., 324(6):E477-E487. [PubMed] [doi] [XPP files] [Commentary on Postić et al, Am. J. Physiol. 2023 324(1):E42-E55 [PubMed]]

  149. L. S. Satin, J. Ha, and A. S. Sherman. 2016. Islets Transplanted into the Eye: Do They Improve Our Insight into Islet Adaptation to Insulin Resistance? Diabetes, 65(9):2470-2. [PubMed] [Commentary on Chen et al, Diabetes. 2016 65(9):2676-85 [PubMed]]

  150. A. Sherman. 2011. Dynamical systems theory in physiology. J. Gen. Physiol. 138:13-19. [PubMed] [Commentary on Cha et al, J. Gen. Physiol. 2011 138(1):39-4765.[PubMed]] [Cover Art]