Lab Website at NIDDK

email: arthurs@niddk.nih.gov


### Journal Articles

  1. J. Ha, R. Muniyappa, A. S. Sherman, and M. J. Quon. 2021. When MINMOD Artifactually Interprets Strong Insulin Secretion as Weak Insulin Action. Frontiers in Physiology. 12:601894. [PubMed] [doi] [XPP and Matlab Files].

  2. R. Jagannathan, C. W. DuBose, L. S. Mabundo, S. T. Chung, J. Ha, A. Sherman, M. Bergman, A. E Sumner. 2020. The OGTT is highly reproducible in Africans for the diagnosis of diabetes: Implications for treatment and protocol design. Diabetes Research and Clinical Practice, 170:108523. [PubMed][doi]

  3. K. Wang, K. Kretschmannova, R.M. Pr'evide, K. Smiljanic, Q. Chen, P.A. Fletcher, A. Sherman, and S.S. Stojilkovic. 2020. Cell Type-Specific Expression Pattern of Proton Sensing Receptors and Channels in Pituitary Gland. Biophys. J., 119(11):2335-2348. [PubMed]

  4. A. F. Hobabagabo, N. H. Osei-Tutu, T. Hormenu, E. M. Shoup, C. W. DuBose, L. S. Mabundo, J. Ha, A. Sherman, S. T. Chung, D. B. Sacks, and A. E. Sumner. 2020. Improved Detection of Abnormal Glucose Tolerance in Africans: The Value of Combining Hemoglobin A 1c With Glycated Albumin. Diabetes Care, 43(10):2607-2613. [PubMed]

  5. R. Muniyappa, H. Chen, M. Montagnani, A. Sherman, and M. Quon. 2020. Endothelial dysfunction due to selective insulin resistance in vascular endothelium: insights from mechanistic modeling. Am. J. Physiol. (Endocrinol. Metab.), 319(3):E629-E646. [PubMed] [Madonna and xpp files]

  6. J. Ha and A. Sherman. 2020. Type 2 Diabetes: One Disease, Many Pathways. Am. J. Physiol. (Endocrinol. Metab.), 319(2):E410-E426. [PubMed] [The Paper] [Matlab and xpp files][Other supplemental material at Figshare] [Highlighted for Diabetes Awareness Month, November, 2020]

  7. S. M. Briker, T. Hormenu, C. W. DuBose, L. S. Mabundo, S. T. Chung, J. Ha, A. Sherman, M. K. Tulloch-Reid, M. Bergman, A. E. Sumner. 2020. Metabolic characteristics of Africans with normal glucose tolerance and elevated 1-hour glucose: insight from the Africans in America study. BMJ Open Diabetes Research and Care. 8(1):e000837. [PubMed]

  8. M. M. Janjic, R. M. Prévide, P. A. Fletcher, A. Sherman, K. Smiljanic, D. Abebe, I. Bjelobaba, and S. S. Stojilkivic. 2019. Divergent expression patterns of pituitary gonadotropin subunit and GnRH receptor genes to continuous GnRH in vitro and in vivo. Sci. Rep. 9(1):20098. [PubMed]

  9. R. T. Scarl, K. L. Corbin, N. W. Vann, H. M. Smith, L. S. Satin, A. Sherman, C. S. Nunemaker. 2019. Intact pancreatic islets and dispersed beta-cells both generate intracellular calcium oscillations but differ in their responsiveness to glucose. Cell Calcium. 83:102081. [PubMed]

  10. P. A. Fletcher, K. Smiljanic, R. Maso Prévide, J. Iben, T. Li, M. B. Rokic, A. Sherman, S. L. Coon, and S. S. Stojilkovic. 2019. Cell Type- and Sex-Dependent Transcriptome Profiles of Rat Anterior Pituitary Cells. Front. Endocrinol. 10:623. [PubMed]

  11. S. Briker, J. Aduwo, R. Mugeni, M. F. Horlyck-Romanovsky, C. DuBose, L. Mabundo, T. Hormenu, S. T. Chung, J. Ha, A. Sherman, and A. E. Sumner. 2019. A1C Underperforms as a Diagnostic Test in Africans even in the Absence of Nutritional Deficiencies, Anemia and Hemoglobinopathies: Insight from the Africans in America Study. Front. Endocrinol., Volume 10, Article 533. [PubMed] [The Paper (Open Access)]

  12. S. T. Chung, M. Galvan-De La Cruz, P. C. Aldana, L. S. Mabundo, C. W. DuBose, A. U. Onuzuruike, M. Walter, A. M. Gharib, A. B. Courville, A. S. Sherman, A. E. Sumner. 2019. Postprandial insulin response and clearance among black and white women: The Federal Women’s Study. J. Clin. Endocrinol. Metab., 104(1):181-192. [PubMed] [Commentary]

  13. S. T. Chung, J. Ha, A. U. Onuzuruike, K. Kasturi, M. Galvan De La Cruz, B. A. Bingham, R. L. Baker, J. N. Utumatwishima, L. S. Mabundo, M. Ricks, A. S. Sherman, A. E. Sumner. 2017. Time to Glucose Peak is a Better Indicator of Prediabetes and β-cell function than Shape of the Glucose Curve. Clin. Endocrinol., 87(5):484-491. [PubMed]

  14. L. Mackay, H. Zemkova, S. S. Stojilkovic, A. Sherman, and A. Khadra. 2017. Deciphering the Regulation of P2X4 Receptor Channel Gating by Ivermectin using Markov Models. PLoS Comp. Biol., 13(7):e1005643. [PubMed]

  15. C. H. Ahn, S. H. Min, D.-W. Lee, T. J. Oh, K. M. Kim, J. H. Moon, S. H. Choi, K. S. Park, H. C. Jang, J. Ha and A. Sherman, and S. Lim. 2017. Hemoglobin Glycation Index Is Associated with Cardiovascular Diseases in People with Impaired Glucose Metabolism. J. Clin. Endocrinol. Metab., 102(8):2905-2913. [PubMed]

  16. J. Ha and A. S. Sherman. 2017. How Adaptation Makes Low Firing Rates Robust. J. Math. Neurosci., 7:4. [PubMed] [The Paper (Open Access)] [xpp files]]

  17. N. R. Gandasi, P. Yin, M. Riz, M. V. Chibalina, G. Cortese, P.-E. Lund, V. Matveev, P. Rorsman, A. Sherman, M. G. Pedersen, and S. Barg. 2017. Ca2+ channel clustering with insulin-containing granules is disturbed in type 2 diabetes. J. Clin. Invest., 127(6):2353-2364. [PubMed]

  18. P. A. Fletcher, H. Zemkova, S. S. Stojilkovic, and A. Sherman. 2017. Modeling the diversity of spontaneous and agonist-induced electrical activity in anterior pituitary corticotrophs. J. Neurophysiol., 117(6):2298-2311. [PubMed] [XPP files]

  19. M. Watts, J. Ha, O. Kimchi, and A. Sherman. 2016. Paracrine Regulation of Glucagon Secretion: The β-α-δ Model. Am. J. Physiol. (Endocrinol. Metab.), 310:E597-E611. [PubMed] [XPP Files]

  20. J. P. McKenna, J. Ha, M. J. Merrins, L. S. Satin, A. Sherman, and R. Bertram. 2016. Ca2+ Effects on ATP Production and Consumption Have Key Regulatory Roles on Oscillatory Islet Activity. Biophys. J., 110(3):733-742. [PubMed] [XPP Files]

  21. M. J. Merrins, C. Poudel, J. P. McKenna, J. Ha, A. Sherman, R. Bertram, and L. S. Satin. 2016. Phase Analysis of Metabolic Oscillations and Membrane Potential in Pancreatic Islet β-cells. Biophys. J., 110(3):691-699. [PubMed]

  22. J. Ha, L. S. Satin and A. S. Sherman. 2016. Mathematical Model of the Pathogenesis, Prevention and Reversal of Type 2 Diabetes. Endocrinology, 157(2):624-635. [PubMed] [XPP Files]

  23. E. Glynn, B. Thompson, S. Lu, S. Vadrevu, R. T. Kennedy, J. Ha, A. Sherman and L. S. Satin. 2016. Chronic glucose exposure systematically shifts the oscillatory threshold of mouse islets: Experimental evidence for an early intrinsic mechanism of compensation for hyperglycemia. Endocrinology, 157(2):611-623. [PubMed]

  24. B. E. Peercy, A. S. Sherman and R. Bertram. 2015. Modeling of glucose-induced cAMP oscillations in pancreatic β-cells: cAMP rocks when metabolism rolls. Biophys. J., 109(2):439-49. [PubMed] [XPP Files (also at journal site)]

  25. H. Zemkova, A. Khadra, M. B. Rokic, V. Tvrdonova, A. Sherman and S. S. Stojilkovic. 2015. Allosteric Regulation of the P2X4 Receptor Channel Pore Dilation. Eur. J. Neurosci. (Pflügers Arch.), 467(4):713-726. [PubMed]

  26. B. Eliasson, U. Smith, S. Mullen, S. W. Cushman, A. S. Sherman and J. Yang. 2014. Amelioration of insulin resistance by rosiglitazone is associated with increased adipose cell size in obese type 2 diabetic patients, Adipocyte 3(4):314-321. [PubMed]

  27. M. Watts, B. Fendler, M. J. Merrins, L. S. Satin, R. Bertram, and A. Sherman. 2014. Calcium and metabolic oscillations in pancreatic islets: Who’s driving the bus? SIAM J. Appl. Dyn. Syst. 13(2):683-703. [PubMed] [doi] [XPP Files]

  28. T. McLaughlin, C. Lamendola, N. Coghlan, T. Liu, K. Lerner, A. Sherman, and S. W. Cushman. 2014. Adipose cell size and distribution: Relationships to insulin resistance, body fat, and sex. Obesity, 22(3):673-80. [PubMed]

  29. M. Watts, and A. Sherman. 2014. Modeling the pancreatic alpha-cell: Dual mechanisms of glucose suppression of glucagon secretion, Biophys. J., 106:741-751. [PubMed] [XPP Files]

  30. J. Ren, A. Sherman, R. Bertram, P. B. Goforth, L. S. Satin, C. Waters and C. Nunemaker. 2013. Slow oscillations of KATP conductance in mouse pancreatic islets provide support for electrical bursting driven by metabolic oscillations. Am. J. Physiol. (Endocrinol. and Metab.), 305(7):E805-17. [PubMed] [XPP and Matlab Files]

  31. A. Khadra, M. Tomić, Z. Yan, H. Zemkova, A. Sherman, and S. S. Stojilkovic. 2013. Dual gating mechanism and function of P2X7 receptor channels, Biophys. J., 104(12):2612-2621. [PubMed]

  32. M. J. Merrins, R. Bertram, A. Sherman, and L. S. Satin. 2012. Phosphofructo-2-kinase/Fructose-2,6-bisphosphatase Modulates Oscillations of Pancreatic Islet Metabolism, PLoS One, 7(4):e34036. [PubMed] [XPP Files]

  33. A. Khadra, Z. Yan, C. Coddou, M. Tomić, A. Sherman, and S. S. Stojilkovic. 2012. Gating properties of the P2X2a and P2X2b receptor channels: Experiments and mathematical modeling. J. Gen. Physiol., 139(5):333-348. [PubMed]

  34. J. Yang, B. Eliasson, U. Smith, S. W. Cushman, and A. Sherman. 2012. The size of large adipose cells is a predictor of insulin resistance in first-degree relatives of type 2 diabetic patients. Obesity, 20(5):932-938. [PubMed]

  35. H. M. Osinga, A. Sherman, and K. Tsaneva-Atanasova. 2012. Cross-currents between biology and mathematics: The codimension of pseudo-plateau bursting. Discrete and Continuous Dynamical Systems A, 32(8):2853-2877. [PubMed]

  36. Z. Yan, A. Khadra, A. Sherman, and S. S. Stojilkovic. 2011. Calcium-dependent block of P2X7 receptor channel function is allosteric. J. Gen. Physiol., 138:(4):437-452. [PubMed]

  37. A. Khadra, M. Pietropaolo, G. T. Nepom, and A. Sherman. 2011. Investigating the role of T cell avidity and killing efficacy in relation to type 1 diabetes prediction PLoS One, 6(5):e14796. [PubMed]

  38. M. Watts, J. Tabak, C. Zimliki, A. Sherman, and R. Bertram. 2011. Slow variable dominance and phase resetting in phantom bursting. J. Theor. Biol. 276:218-228. [PubMed] [XPP Files]

  39. A. Liu, A. Sonmez, G. Yee, M. Bazuine, M. Arroyo, A. Sherman, T. McLaughlin, G. Reaven, s. Cushman, P. Tsao. 2010. Differential adipogenic and inflammatory properties of small adipocytes in Zucker Obese and Lean rats. Diab Vasc Dis Res., 7(4):311-8. [PubMed]

  40. Z. Yan, A. Khadra, S. Li, M. Tomic, A. Sherman, and S. S. Stojilkovic. 2010. Experimental characterization and mathematical modeling of P2X7 receptor channel gating. J Neurosci. 30(42):14213-24. [PubMed]

  41. R. Kursawe, M. Eszlinger, D. Narayan, T. Liu, M. Bazuine, A. M. G. Cali, M. Shaw, B. Pierpont, G. I. Shulman, S. W. Cushman, A. Sherman, and S. Caprio. 2010. Cellularity and adipogenic profile of the abdominal subcutaneous adipose tissue from obese adolescents: association with insulin resistance and hepatic steatosis. Diabetes, 59(9):2288-96. [PubMed]

  42. B. E. Peercy and A. S. Sherman. 2010. How pancreatic beta-cells distinguish long- and short-time scale cAMP signals. Biophys. J., 99(2):398-406 [PubMed] [XPP and Matlab Files]

  43. M. J. Merrins, B. Fendler, M. Zhang, A. Sherman, R. Bertram, and L. S. Satin. 2010. Metabolic oscillations in pancreatic islets depend on the intracellular Ca2+ level but not Ca2+ oscillations, Biophys. J., 99:(1)76-94. [PubMed] [XPP Files]

  44. K. Tsaneva-Atanasova, H. M. Osinga, T. Riess, and A. Sherman. 2010. Full system bifurcation analysis of endocrine bursting models. J. Theor. Biol., 264:1133-1146. [PubMed]

  45. T. McLaughlin, G. Yee, T. Liu, F. Abbasi, C. Lamendola, G. Reaven, P. Tsao, S. W. Cushman, and A. Sherman. 2010. Pioglitazone increases the proportion of small cells in human subcutaneous abdominal adipose tissue. Obesity, 18(5):926-31. [PubMed]

  46. T. McLaughlin, A. Deng, G. Yee, C. Lamendola, G. Reaven, P. S. Tsao, S. W. Cushman, and A. Sherman. 2010. Inflammation in subcutaneous adipose tissue: relationship to adipose cell size. Diabetologia 53(2):369-377. [PubMed] [Commentary]

  47. C. S. Nunemaker, J. F. Dishinger, S. B. Dula, R. Wu, M. M. Merrins, K. R. Reid, A. Sherman, R. T. Kennedy, and L. S. Satin. 2009. Glucose metabolism, islet architecture, and genetic homogeneity in imprinting of [C a2+]i and insulin rhythms in mouse islets. PloS One, 4(12):e8428. [PubMed]

  48. A. Liu, T. McLaughlin, T. Liu, A. Sherman, G. Yee, F. Abbasi, C. Lamendola, J. Morton, S. W. Cushman, G. M. Reaven, and P. S. Tsao. 2009 Differential Intra-abdominal Adipose Tissue Profiling in Obese, Insulin-resistant Women. Obes. Surg., 19(11):1564-73. [PubMed]

  49. P. Goel and A. Sherman. 2009. The geometry of bursting in the dual oscillator model of pancreatic beta-cells. SIAM Journal on Applied Dynamical Systems, 8(4):1664-1693. [doi]

  50. V. Matveev, R. Bertram, and A. Sherman. 2009. Ca2+ current vs. Ca2+ channel cooperativity of exocytosis. J. Neurosci., 29(39):12196-12209. [PubMed] [CalC Scripts]

  51. K. Tsaneva-Atanasova and A. Sherman. 2009. Accounting for near-normal glucose sensitivity in Kir6.2[AAA] transgenic mice. Biophys. J. 97(9):2409-18. [PubMed]

  52. P. Goel, A. Sherman, and A. Friedman. 2009. Multiscale modeling of electrical and intracellular activity in the pancreas: The islet tridomain equations. Multiscale Model. Simul., 7(4):1609-1642. [doi]

  53. M. G. Pedersen and A. Sherman. 2009. Newcomer insulin secretory granules as a highly calcium-sensitive pool. PNAS 106(18):7432-6. [PubMed] [xpp files]

  54. T. McLaughlin, A. Deng, O. Gonzales, M. Aillaud, G. Yee, C. Lamendola, F. Abbasi, A. J. Connolly, A. Sherman, S. W. Cushman, G. Reaven, P. S. Tsao. 2008. Insulin resistance is associated with a modest increase in inflammation in subcutaneous adipose tissue of moderately obese women. Diabetologia, 51:2303-8. [PubMed]

  55. M. Zhang, B. Fendler, B. Peercy, P. Goel, R. Bertram, A. S. Sherman, and L. S. Satin. 2008. Long lasting synchronization of calcium oscillations by cholinergic stimulation in isolated pancreatic islets. Biophys. J., 95:4676-4688. [PubMed] [XPP Files]

  56. Y. D. Chen, S. Wang, A. Sherman. 2008. Identifying the targets of the amplifying pathway for insulin secretion in pancreatic beta-cells by kinetic modeling of granule exocytosis. Biophys. J. 95(5):2226-41. [PubMed] [XPP Files]

  57. J. V. Stern, H. M. Osinga, A. LeBeau, and A. Sherman. 2008. Resetting behavior in a model of bursting in secretory pituitary cells: Distinguishing plateaus from pseudo-plateaus. Bull. Math. Biol., 70(1):68-88. [PubMed] [XPP Files]

  58. K. Tsaneva-Atanasova, A. Sherman, F. van Goor, and S. S. Stojilkovic. 2007. Mechanism of spontaneous and receptor-controlled electrical activity in pituitary somatotrophs: Experiments and theory. J. Neurophysiol. 98(1):131-44. [PubMed] [XPP File]

  59. T. McLaughlin, A. Sherman, P. Tsao, O. Gonzalez, G. Yee, C. Lamendola, G. M. Reaven, and S. W. Cushman. 2007. Enhanced proportion of small adipose cells in insulin-resistant versus insulin-sensitive obese individuals implicates impaired adipogenesis. Diabetologia, 50(8):1707-15. [PubMed]

  60. H. L. Ong, X. Liu, K. Tsaneva-Atanasova, B. B. Singh, B. C. Bandyopadhyay, W. D. Swaim, J. T. Russell, R. S. Hegde, A. Sherman, and I. S. Ambudkar. 2007. Relocalization of STIM1 for activation of store-operated Ca2+ entry is determined by the depletion of subplasma membrane endoplasmic reticulum Ca2+ store. J. Biol. Chem., 282(16):12176-85. [PubMed]

  61. R. Bertram, L. S. Satin, M. Gram Pedersen, D. S. Luciani, and A. Sherman, 2007. Interaction of glycolysis and mitochondrial respiration in metabolic oscillations of pancreatic islets. Biophys. J., 92(5):1544-55. [Pubmed] [XPP files]

  62. V. Matveev, R. Bertram, and A. Sherman, 2006. Residual bound Ca2+ can account for the effects of Ca2+ buffers on synaptic facilitation., J. Neurophysiol. 96(6):3389-97 [Pubmed] [CalC Scripts]

  63. R. Bertram, M. Gram Pedersen, D. S. Luciani, and A. Sherman, 2006. A simplified model for mitochondrial ATP production, J. Theor. Biol., 243(4):575-86. [Pubmed] [XPP file]

  64. C. S. Nunemaker, R. Bertram, A. Sherman, K. Tsaneva-Atanosova, C. R. Daniel, and L. S. Satin. 2006. Glucose modulates Ca2+ oscillations in pancreatic islets via ionic and glycolytic mechanisms, Biophys. J., 91:2082-2096. [Pubmed] [XPP Files]

  65. K. Tsaneva-Atanasova, C. L. Zimliki, R. Bertram, and A. Sherman, 2006. Diffusion of calcium and metabolites in pancreatic islets: Killing oscillations with a pitchfork, Biophys. J., 90:3434-3446. [PubMed] [XPP Files]

  66. C. S. Nunemaker, M. Zhang, D. H. Wasserman, O. P. McGuinness, A. C. Powers, R. Bertram, A. Sherman, and L. S. Satin, 2005. Individual mice can be distinguished by the period of their islet calcium oscillations: Is there an intrinsic islet period which is imprinted in vivo? Diabetes, 54:3517-3522 [PubMed]

  67. M. G. Pedersen, R. Bertram, and A. Sherman. 2005. Intra- and Inter-Islet Synchronization of Metabolically Driven Insulin Secretion, Biophys. J., 89:107-119. [PubMed] [XPP Files]

  68. R. Bertram and A. Sherman. 2004. Filtering of calcium transients by the endoplasmic reticulum in pancreatic beta-cells, Biophys. J., 87:3775-3785. [PubMed] [XPP Files]

  69. R. Bertram, L. Satin, M. Zhang, P. Smolen, and A. Sherman. 2004. Calcium and glycolysis mediate multiple bursting modes in pancreatic islets, Biophys. J., 87:3074-3087. [PubMed] [XPP Files and Errata]

  70. R. Bertram and A. Sherman. 2004. A calcium based phantom bursting model for pancreatic beta-cells, Bull. Math. Biol., 66:1313-1344. [PubMed][XPP and Matlab Files]

  71. C. Zimliki, D. Mears, and A. Sherman. 2004. Three roads to islet bursting: Emergent oscillations in coupled phantom bursters, Biophys. J., 87:193-206. [PubMed][XPP file]

  72. V. Matveev, R. S. Zucker, and A. Sherman. 2004. Facilitation through buffer saturation: Constraints on endogenous buffering properties,. Biophys. J. 86:2691-2709. [PubMed] [Calcium Calculator Scripts]

  73. M. Zhang, P. Goforth, A. Sherman, R. Bertram, and L. S. Satin. 2003. The Ca2+ dynamics of isolated mouse beta-cells and islets: Implications for mathematical models, . Biophys. J. 84:2852-2870. [PubMed] [XPP Files]

  74. A. R. Sedaghat, A. Sherman, and M. J. Quon. 2002. A mathematical model of metabolic insulin signaling pathways, Am. J. Physiol. (Endocrinol. Metab.), 283:E1084-E1101. [PubMed] [Supplementary Material: XPP/WinPP Differential Equation Files]

  75. P. B. Goforth, R. Bertram, F. A. Khan, M. Zhang, A. Sherman, and L. S. Satin. 2002. Calcium-activated K+ channels of mouse pancreatic beta-cells are controlled by both store and cytoplasmic Ca2+. J. Gen. Physiol., 120:307-322. [PubMed] [XPP Files]

  76. V. Matveev, A. Sherman, and R. S. Zucker. 2002. New and Corrected Simulations of Synaptic Facilitation, Biophys. J., 83:1368-73. [PubMed] [Simulation Software]

  77. G. de Vries and A. Sherman. 2001. From spikers to bursters via coupling: Help from heterogeneity, Bull. Math. Biol., 63:371-391. [PubMed]

  78. G. D. Smith, L.-X. Dai, R. Miura, and A. Sherman. 2001. Asymptotic analysis of equations for the buffered diffusion of intracellular calcium. SIAM J. Applied Math., 61:1816-1838. [doi] [Matlab Files]

  79. A. P. LeBeau, F. Van Goor, S. S. Stojilkovic, and A. Sherman. 2000. Modeling of membrane excitability in gonadotropin-releasing hormone-secreting hypothalamic neurons regulated by Ca2+-mobilizing and adenylyl cyclase-coupled receptors. J. Neurosci., 20:9290-9297. [PubMed]

  80. G. de Vries and A. Sherman. 2000. Channel sharing in pancreatic beta-cells revisited: Enhancement of emergent bursting by noise. J. Theor. Biol., 207:513-530. [PubMed]

  81. R. Bertram, J. Previte, A. Sherman, T. A. Kinard, and L. S. Satin. 2000. The phantom burster model for pancreatic beta-cells. Biophys. J., 79:2880-2892. [PubMed] [XPP File]

  82. F. Van Goor, A. P. LeBeau, L. Z. Krsmanovic, A. Sherman, K. J. Catt, and S. S. Stojilkovic. 2000. Amplitude-dependent spike-broadening in immortalized GnRH neurons. Biophys. J., 79:1310-1323. [PubMed]

  83. T. A. Kinard, G. de Vries, A. Sherman, and L. S. Satin. 1999. Modulation of the bursting properties of single mouse pancreatic beta-cells by artificial conductances. Biophys. J., 76:1423-1435. [PubMed]

  84. R. Bertram, G. D. Smith, and A. Sherman. 1999. A modeling study of the effects of overlapping Ca2+ microdomains on neurotransmitter release. Biophys. J., 76:735-750. [[PubMed](https://pubmed.ncbi.nlm.nih.gov/9929478/]

  85. G. de Vries, H.-R. Zhu, and A. Sherman. 1998. Diffusively coupled bursters: Effects of heterogeneity. Bull. Math. Biol., 60:1167-1200. [PubMed] [Mathematica Files]

  86. R. Bertram and A. Sherman. 1998. Population dynamics of synaptic release sites. SIAM J. Applied Math., 58:142-169. [doi]

  87. D. Mears, N. F. Sheppard, Jr., I. Atwater, E. Rojas, R. Bertram, and A. Sherman. 1997. Evidence that calcium release-activated current mediates transient glucose-induced electrical activity in the pancreatic beta-cell. J. Membr. Bio., 155:47-59.  [PubMed] [XPP File]

  88. R. Bertram, A. Sherman, and E. Stanley. 1996. The single domain/bound calcium hypothesis of transmitter release and facilitation. J. Neurophysiol., 75:1919-1931.  [PubMed] [XPP File]

  89. R. Bertram, P. Smolen, A. Sherman, D. Mears, I. Atwater, F. Martin, and B. Soria. 1995. A role for calcium-release activated current (CRAC) in cholinergic modulation of electrical activity in pancreatic beta-cells. Biophys. J. 68:2323-2332. [PubMed] [XPP File]

  90. R. Bertram, M. Butte, T. Kiemel, and A. Sherman. 1995. Topological and phenomenological classification of bursting mechanisms. Bull. Math. Biol. 57:413-439. [PubMed] [XPP File]

  91. A. Sherman, L. Xu, and C. Stokes. 1995. Estimating and eliminating junctional current in coupled cell populations by leak subtraction. A computational study. J. Membr. Biol., 143:79-87. [PubMed]  (Joint with experimental paper: E. Rojas, C. Stokes, D. Mears, and I. Atwater. 1995. Single micro-electrode voltage-clamp measurements of pancreatic beta-cell membrane ionic currents in intact mouse islets of Langerhans. J. Membr. Biol. 143:65-77).  [PubMed]

  92. A. Sherman and M. Mascagni. 1994. A gradient random walk method for two-dimensional reaction-diffusion equations. SIAM J. Sci. Comput. 15:1280-1293. [doi]

  93. P. Smolen and A. Sherman. 1994. Phase-independent resetting in relaxation and burst oscillators. J. Theor. Biol. 169:339-348. [PubMed] [XPP File]

  94. A. Sherman. 1994. Anti-phase, asymmetric, and aperiodic oscillations in excitable cells I. Coupled bursters. Bull. Math. Biol. 56:811-835.  [PubMed] [XPP File]

  95. P. Smolen, J. Rinzel, and A. Sherman. 1993. Why pancreatic islets burst but single beta-cells do not: The heterogeneity hypothesis. Biophys. J. 64:1668-1680.   [PubMed]

  96. A. Sherman and J. Rinzel. 1992. Rhythmogenic effects of weak electrotonic coupling in neuronal models. Proc. Natl. Acad. Sci. USA. 89:2471-2474.  [PubMed] [XPP Files]

  97. A. Sherman and J. Rinzel. 1991. Model for synchronization of pancreatic beta-cells by gap junction coupling. Biophys. J. 59:547-559.  [PubMed]

  98. A. Sherman, J. Keizer, and J. Rinzel. 1990. Domain model for Ca2+ inactivation of Ca2+ channels at low channel density. Biophys. J. 58:985-995.  [PubMed] [XPP File]

  99. P. B. Carroll, A. Sherman, R. Ferrer, A. C. Boschero, J. Rinzel, and I. Atwater. 1990. Modulation of the frequency of glucose-dependent bursts of electrical activity by HCO3/CO2 in rodent pancreatic beta-cells. Experimental and theoretical results. Eur. Biophys. J. 18:71-77.  [PubMed]

  100. A. Sherman, J. Rinzel, and J. Keizer. 1988. Emergence of organized bursting in clusters of pancreatic beta-cells by channel sharing. Biophys. J. 54:411-425.   [PubMed] [XPP File]

  101. A. S. Sherman and C. S. Peskin. 1988. Solving the Hodgkin-Huxley equations by a random walk method. SIAM J. Sci. and Stat. Comput. 9:170-190.  [doi]

  102. A. S. Sherman and C. S. Peskin. 1986. A Monte Carlo method for scalar reaction diffusion equations. SIAM J. Sci. and Stat. Comput. 7:1360-1372. [doi]

    Invited Reviews

  103. R. Bertram, L. S. Satin, and A. S. Sherman. 2018. Closing in on the mechanisms of pulsatile insulin secretion. Diabetes, 67:351-359. [PubMed]. [XPP File]

  104. P. A. Fletcher, A. Sherman, and S. S. Stojilkovic. 2018. Common and diverse elements of ion channels and receptors underlying electrical activity in endocrine pituitary cells. Molecular and Cellular Endocrinology, 463:23 - 36. [PubMed] [XPP files]

  105. L. S. Satin, P. C. Butler, J. Ha, and A. Sherman. 2015. Pulsatile insulin secretion, impaired glucose tolerance and type 2 diabetes. Journal of Molecular Aspects of Medicine, 42:61-77. [PubMed]

  106. V. Matveev, R. Bertram, and A. Sherman, 2011. Calcium cooperativity of exocytosis as a measure of Ca2+ channel domain overlap. Brain Research Reviews, 1398:126-128. [PubMed]

  107. A. Sherman, 2010. Lessons from Models of Pancreatic beta Cells for Engineering Glucose-sensing Cells. Math. Biosci., 227:12-19. [PubMed]

  108. R. Bertram, A. Sherman, and L. S. Satin, 2007. Metabolic and electrical oscillations: Partners in controlling pulsatile insulin secretion. Am. J. Physiol. Endocrinol. Metab. 293:890-900. [PubMed]. [XPP File]

  109. G. de Vries and A. Sherman. 2005. Beyond Synchronization: Modulatory and Emergent Effects of Coupling in Square-Wave Bursting in “Bursting: The Genesis of Rhythm in the Nervous System”, World Scientific, London, pp. 243-272. [Publisher’s Site] [doi]

  110. R. Bertram and A. Sherman. 2005. Negative Calcium Feedback: The Road from Chay-Keizer in “Bursting: The Genesis of Rhythm in the Nervous System”, S. Coombes and P. Bressloff, eds., World Scientific, London, pp. 19-48. [Publisher’s Site][doi]

  111. A. Sherman and R. Bertram. 2005. Integrative Modeling of the Pancreatic beta-Cell. in “Wiley Interscience Encyclopedia of Genetics, Genomics, Proteomics, and Bioinformatics”, Part 3 Proteomics, M. Dunn, ed., Section 3.8 Systems Biology, R. L. Winslow, ed., John Wiley & Sons, Ltd. DOI: 10.1002/047001153X.g308213. [On-Line Book] [XPP Files]

  112. A. Sherman. 1996. Contributions of modeling to understanding stimulus-secretion coupling in pancreatic beta-cells. Am. J. Physiol. 271 (Endocrinol. Metab. 34): E362-E372. [PubMed] [XPP File]

  113. A. Sherman. 1995. Theoretical aspects of synchronized bursting in beta-cells, in Pacemaker Activity and Intercellular Communication, J. D. Huizinga, ed., CRC Press, Boca Raton, pp. 323-337.

    Book Chapters & Other Reviews

  114. L. S. Satin, M. Watts, and A. Sherman. 2020. An introduction to beta cell electrophysiology and modeling, in Diabetes System Biology: Quantitative methods for understanding beta-cell dynamics and function, A. Khadra, editor. IOP Publishing, Bristol, UK, pp. 2-1 - 2-46. [doi] [XPP and Matlab Files]

  115. A. Sherman. 2016. Endoplasmic reticulum- and plasma membrane-driven calcium oscillations, in “Computational Neuroendocrinology” (Wiley-INF Masterclass in Neuroendocrinology Series), D. J. MacGregor and G. Leng, eds., John Wiley & Sons, Chichester, UK, p. 112-141. [The Book] [doi]

  116. R. Bertram, A. Sherman, and L. S. Satin. 2013. Electrical, Calcium, and Metabolic Oscillations in Pancreatic Islets, in “The Islets of Langerhans”, 2nd edition, M. S. Islam, ed., Springer-Verlag, Berlin, p. 453-474. [doi] [The Book]

  117. R. Bertram, A. Sherman, and L. S. Satin. 2010. Electrical Bursting, Calcium Oscillations, and Synchronization of Pancreatic Islets, in “The Islets of Langerhans”, M. S. Islam, ed., Springer-Verlag, Berlin, (Adv Exp Med Biol, 654:261-79). [PubMed] [doi]

  118. R. Bertram, K. Wierschem, M. Zhang, P. Goforth, A. Sherman, and L. S. Satin. 2002. Phantom bursting in pancreatic islets: A potential role for insulin feedback, in “Recent Research Developments in Biophysics”, S. G. Pandalai, ed., Transworld Research Network, Vol. 1, pp. 31-51.

  119. A. Sherman, Y.-X. Li, and J. Keizer. 2002. Whole Cell Models in “Computational Cell Biology”, C. Fall, E. Marland, J. Wagner, and J. Tyson , eds., Springer-Verlag, New York, pp. 101 - 139. [Publisher Site for the Book] [XPP Files]

  120. R. Bertram and A. Sherman. 2000. Dynamical complexity and temporal plasticity in pancreatic beta-cells. J. Biosc., 25:197-209. [PubMed]

  121. M. V. Mascagni and A. S. Sherman. 1998. Numerical methods for neuronal modeling, in “Methods in Neuronal Modeling,” I. Segev and C. Koch, eds., MIT Press, Cambridge, pp.569-606. [The Book] [Supplementary Material]

  122. A. Sherman and P. Smolen. 1997. Computer modeling of heterogeneous beta-cell populations, in “Physiology and Pathophysiology of the Islets of Langerhans”, B. Soria, ed., Plenum Press, New York, pp. 275-284. [PubMed] [doi]

  123. A. Sherman. 1997. Calcium and membrane potential oscillations in pancreatic beta-cells, in “Case Studies in Mathematical Modeling - Ecology, Physiology, and Cell Biology”, H. G. Othmer, F. R. Adler, M. A. Lewis, and J. C. Dallon, eds., Prentice-Hall, New Jersey, p. 199 - 217. [The Book] [Models and Exercises]

  124. J. Rinzel, A. Sherman, and C. L. Stokes. 1992. Channels, coupling, and synchronized rhythmic bursting activity. in “Analysis and Modeling of Neural Systems”, F. H. Eeckman, ed., Kluwer Academic Publishers, Boston, pp. 29-46.

  125. A. Sherman, P. Carroll, R. Santos, and I. Atwater. 1990. Glucose dose response of pancreatic beta-cells: Experimental and theoretical results, in “Transduction in Biological Systems”, J. Bacigalupo, C. Hidalgo, E. Jaimovich, and J. Vergara, eds., Plenum Press, New York, pp. 123-141.

  126. A. Sherman and J. Rinzel. 1989. Collective properties of insulin secreting cells, in “Cell to Cell Signalling: From Experiments to Theoretical Models”, A. Goldbeter, ed., Academic Press, London, pp. 61-75.

    Commentary

  127. L. S. Satin, J. Ha, and A. S. Sherman. 2016. Islets Transplanted into the Eye: Do They Improve Our Insight into Islet Adaptation to Insulin Resistance? Diabetes, 65(9):2470-2. [PubMed] [Commentary on Chen et al, Diabetes. 2016 65(9):2676-85]

  128. A. Sherman. 2011. Dynamical systems theory in physiology. J. Gen. Physiol. 138:13-19. [PubMed] [Commentary on Cha et al, J. Gen. Physiol. 2011 138(1):39-4765.] [Cover Art]